Small molecule-triggered assembly of DNA nanoarchitectures

Chem Commun (Camb). 2010 Mar 21;46(11):1866-8. doi: 10.1039/b921481j. Epub 2010 Jan 13.

Abstract

The utilization of toehold-containing DNA strands allows for the assembly of complex nanostructures via kinetically driven hybridization reactions. Here, we have rendered this strategy ligand-dependent, resulting in small-molecule-inducible DNA nanoarchitectures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aptamers, Nucleotide / chemistry
  • Arginine / chemistry
  • DNA / chemistry*
  • Nanostructures / chemistry*
  • Nucleic Acid Conformation
  • Nucleic Acid Hybridization

Substances

  • Aptamers, Nucleotide
  • DNA
  • Arginine