Unique CT imaging findings of liver in Wilson's disease

Abdom Imaging. 2011 Feb;36(1):69-73. doi: 10.1007/s00261-010-9606-8.

Abstract

Purpose: To present unique CT imaging findings of the liver in Wilson's disease.

Materials and methods: Thirteen consecutive subjects with clinically and/or pathologically proven Wilson's disease underwent abdominal Computer Tomography examination.

Results: Hyperdense nodules and a honeycomb appearance were observed on unenhanced CT in 92.31 and 58.33% of our patients, respectively.

Conclusion: Wilson's disease involving the liver has several unique CT findings in comparison to other types of cirrhosis. These specific features include hyperdense nodules and a honeycomb pattern not only in portal and parenchymal phases, but also in the pre-contrast scan.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Female
  • Hepatolenticular Degeneration / diagnostic imaging*
  • Humans
  • Liver / diagnostic imaging*
  • Male
  • Observer Variation
  • Tomography, X-Ray Computed / methods*
  • Young Adult