Abstract
The first synthesis of adicardin, a compound with anti-chronic renal failure activity isolated from Hydrangea macrophylla, has been described. The structures of the target compound and intermediates have been validated by MS, NMR, and identical with the natural product.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Glucosides / chemical synthesis*
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Glucosides / chemistry
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Glucosides / pharmacology
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Hydrangea / chemistry*
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Kidney Failure, Chronic / drug therapy*
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Molecular Structure
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Stereoisomerism
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Umbelliferones / chemical synthesis*
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Umbelliferones / chemistry
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Umbelliferones / pharmacology
Substances
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Glucosides
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Umbelliferones
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adicardin