Two new lignans from Phyllanthus amarus

J Asian Nat Prod Res. 2009 Jun;11(6):562-8. doi: 10.1080/10286020902939174.

Abstract

Two new lignans, 3-(3,4-dimethoxy-benzyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl-methyl)-dihydrofuran-2-one (1) and 4-(3,4-dimethoxy-phenyl)-1-(7-methoxy-benzo[1,3]dioxol-5-yl)-2,3-bis-methoxymethyl-butan-1-ol (2), were isolated from the leaves of Phyllanthus amarus and their structures were established by spectral analysis. Additionally, eight known lignans were also isolated and characterized.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Butyrolactone / analogs & derivatives*
  • 4-Butyrolactone / chemistry
  • 4-Butyrolactone / isolation & purification*
  • India
  • Lignans / chemistry
  • Lignans / isolation & purification*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Phyllanthus / chemistry*
  • Plant Leaves / chemistry

Substances

  • 3-(3,4-dimethoxy-benzyl)-4-(7-methoxy-benzo(1,3)dioxol-5-yl-methyl)-dihydrofuran-2-one
  • 4-(3,4-dimethoxy-phenyl)-1-(7-methoxy-benzo(1,3)dioxol-5-yl)-2,3-bis-methoxymethyl-butan-1-ol
  • Lignans
  • 4-Butyrolactone