Abstract
Here we demonstrate the use of redox labeled double- and single-stranded oligonucleotides as recognition probes for the reagentless, single-step, electrochemical detection of anti-DNA antibodies directly in blood serum.
MeSH terms
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Animals
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Antibodies / blood*
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Antibodies / chemistry
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Antibodies / immunology*
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Blood Chemical Analysis / methods*
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Cattle
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DNA / chemistry
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DNA / immunology*
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DNA Probes / chemistry
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DNA Probes / immunology
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Electrochemistry
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Electrodes
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Gold / chemistry
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Immunoassay
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Limit of Detection
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Models, Molecular
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Nucleic Acid Conformation
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Point-of-Care Systems
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Protein Conformation
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Time Factors
Substances
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Antibodies
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DNA Probes
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Gold
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DNA