Two new prenylated xanthones and a new prenylated tetrahydroxanthone, garcimangosxanthone A-C (1-3), along with fourteen known xanthones were isolated from the pericarp of Garcinia mangostana. Their structures were elucidated on the basis of spectroscopic data. Compounds 1 and 2 exhibited in vitro cytotoxicity against A549, LAC and A375 cell lines with IC(50) values of 5.7-24.9 microM, which were comparable to those of doxorubicin.
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