Emerging applications of nanomedicine for the diagnosis and treatment of cardiovascular diseases

Trends Pharmacol Sci. 2010 May;31(5):199-205. doi: 10.1016/j.tips.2010.01.003. Epub 2010 Feb 19.

Abstract

Nanomedicine is an emerging field that utilizes nanotechnology concepts for advanced therapy and diagnostics. This convergent discipline merges research areas such as chemistry, biology, physics, mathematics and engineering. It therefore bridges the gap between molecular and cellular interactions, and has the potential to revolutionize medicine. This review presents recent developments in nanomedicine research poised to have an important impact on the treatment of cardiovascular disease. This will occur through improvement of the diagnosis and therapy of cardiovascular disorders as atherosclerosis, restenosis and myocardial infarction. Specifically, we discuss the use of nanoparticles for molecular imaging and advanced therapeutics, specially designed drug eluting stents and in vivo/ex vivo early detection techniques.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / drug therapy*
  • Diagnostic Imaging / methods
  • Drug-Eluting Stents
  • Early Diagnosis
  • Humans
  • Nanomedicine / methods*
  • Nanoparticles* / therapeutic use