Ectopic ossification with haematopoietic bone marrow in the heart valves of a crossbred heavy horse

J Comp Pathol. 2010 Aug-Oct;143(2-3):213-7. doi: 10.1016/j.jcpa.2010.01.013. Epub 2010 Feb 18.

Abstract

Ectopic bone formation in the left atrioventricular valves and cardiac fibroskeleton, with systemic circulatory disturbance, is reported in a 4-year-old crossbred heavy horse. Microscopically, there was fibrosis, chondral metaplasia and mature bone, with bone marrow within the left atrioventricular cusps and in the annuli of the aortic and right atrioventricular valves.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Animals, Inbred Strains
  • Bone and Bones / pathology
  • Female
  • Fibrosis
  • Heart Atria / pathology
  • Heart Valve Diseases / pathology
  • Heart Valve Diseases / veterinary*
  • Heart Valves / pathology*
  • Heart Ventricles / pathology
  • Hematopoietic Stem Cells / pathology*
  • Horse Diseases / pathology*
  • Horses
  • Hybridization, Genetic
  • Metaplasia / pathology
  • Ossification, Heterotopic / pathology*