TPR motifs: hallmarks of a new polysaccharide export scaffold

Chris Whitfield; Iain L Mainprize

doi:10.1016/j.str.2010.01.006

TPR motifs: hallmarks of a new polysaccharide export scaffold

Structure. 2010 Feb 10;18(2):151-3. doi: 10.1016/j.str.2010.01.006.

Authors

Chris Whitfield, Iain L Mainprize

PMID: 20159460
DOI: 10.1016/j.str.2010.01.006

Abstract

Bacteria produce a remarkable range of surface and secreted polysaccharides. Two pathways have been defined for the biosynthesis and export of capsular polysaccharides and exopolysaccharides in Gram-negative bacteria. A structure of AlgK described in this issue provides structural insight into a third previously unrecognized pathway associated with important biopolymers (Keiski et al., 2010).

Publication types

Comment
News

MeSH terms

Amino Acid Motifs
Bacterial Capsules / chemistry
Bacterial Proteins* / chemistry
Bacterial Proteins* / genetics
Bacterial Proteins* / metabolism
Gram-Negative Bacteria / metabolism*
Models, Molecular
Polysaccharides, Bacterial / chemistry
Polysaccharides, Bacterial / metabolism*
Protein Conformation

Substances

AlgK protein, Pseudomonas aeruginosa
Bacterial Proteins
Polysaccharides, Bacterial