Previous research has been equivocal as to the impact of smoking status on cardiovascular reactivity to challenge. In addition, little is known about patterns of cardiovascular response habituation-sensitization to repeated challenge, in either smokers or the general population as a whole. The present study sought to clarify whether smokers and non-smokers differ in cardiovascular reactivity to challenge, or in patterns of reactivity to repeated challenge. 28 smokers and 28 anthropometrically matched non-smokers underwent repeated cardiovascular reactivity assessment. Results suggest that smokers had higher diastolic blood pressure (DBP) than non-smokers, and that female non-smokers demonstrated DBP response sensitization. Findings highlight direct associations between smoking and cardiovascular reactivity of potential significance to the etiology of cardiovascular disease.
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