Synthesis of thia-analogous indirubin N-Glycosides and their influence on melanoma cell growth and apoptosis

ChemMedChem. 2010 Apr 6;5(4):534-9. doi: 10.1002/cmdc.200900506.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemical synthesis*
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / therapeutic use
  • Apoptosis*
  • Cell Line, Tumor
  • Glycosides / chemical synthesis
  • Glycosides / chemistry*
  • Glycosides / therapeutic use
  • Humans
  • Indoles / chemistry
  • Intracellular Signaling Peptides and Proteins / metabolism
  • Melanoma / drug therapy*
  • Melanoma / pathology
  • Phosphatidylinositol 3-Kinases / metabolism
  • Protein Serine-Threonine Kinases / metabolism
  • TOR Serine-Threonine Kinases

Substances

  • Antineoplastic Agents
  • Glycosides
  • Indoles
  • Intracellular Signaling Peptides and Proteins
  • MTOR protein, human
  • Protein Serine-Threonine Kinases
  • TOR Serine-Threonine Kinases
  • indirubin