Retinal complications of juvenile idiopathic arthritis-related uveitis: a microperimetry and optical coherence tomography study

Ocul Immunol Inflamm. 2010 Jan;18(1):54-9. doi: 10.3109/09273940903311999.

Abstract

Purpose: To evaluate ocular complications of juvenile idiopathic arthritis (JIA)-related uveitis; to study macular morphology and sensitivity.

Methods: Retrospective chart review of 67 patients. Fourteen consecutive patients (24 eyes) observed from January to December 2008 were submitted to optical coherence tomography study (OCT) and microperimetry MP-1 examination.

Results: Most frequent complications were posterior synechiae (63.0%), band keratopathy (53.9%), and cataract (31.8%). Posterior complications were documented in 37.0% of eyes: 13.8% macular edema, 12.0% papillitis, 6.8% epiretinal membranes, 2.5% retinal vasculitis, 1.7% retinal detachment. At OCT examination 25.0% of eyes presented macular edema; macular sensitivity by MP-1 was < or = 16.5 dB in 25.0% of eyes.

Conclusions: Visual prognosis is good despite ocular complications. Incidence of macular edema seems to be higher when using OCT. Microperimetry may represent a useful tool in detecting alteration in retinal sensitivity that may supplement visual acuity in the follow-up of macular edema.

MeSH terms

  • Adolescent
  • Arthritis, Juvenile / complications*
  • Arthritis, Juvenile / pathology
  • Child
  • Eye Diseases / diagnosis
  • Eye Diseases / epidemiology
  • Eye Diseases / etiology
  • Female
  • Humans
  • Incidence
  • Macular Edema / diagnosis*
  • Macular Edema / epidemiology*
  • Macular Edema / etiology
  • Male
  • Retinal Detachment / diagnosis
  • Retinal Detachment / epidemiology
  • Retinal Detachment / etiology
  • Retrospective Studies
  • Tomography, Optical Coherence*
  • Uveitis / complications*
  • Uveitis / pathology
  • Visual Field Tests / methods*