Transpupillary thermotherapy of subfoveal choroidal neovascularization secondary to pathologic myopia

Ophthalmic Surg Lasers Imaging. 2010 Jan-Feb;41(1):12-7. doi: 10.3928/15428877-20091230-02.

Abstract

Background and objective: To assess the safety and effectiveness of transpupillary thermotherapy treatment of subfoveal choroidal neovascular membrane secondary to pathologic myopia.

Patients and methods: Seventy-four patients (74 eyes) with pathologic myopia underwent transpupillary thermotherapy treatment using a 3.0-mm spot size, 1-minute duration, and 520-mW power delivered through a contact lens. Clinical evaluation included measurement of best-corrected Snellen visual acuity, slit-lamp biomicroscopy, fundus color photography, and fluorescein angiography.

Results: Sixty-four eyes (86%) received one treatment session. Six eyes (8%) improved 0.1 logarithm of the minimum angle of resolution (LogMAR) visual acuity post-treatment, 10 eyes (13.5%) lost more than 0.2 LogMAR acuity, and another 10 eyes (13.5%) lost 0.1 LogMAR acuity. The remaining 48 eyes (65%) had unchanged visual acuity after the last follow-up visit.

Conclusion: Transpupillary thermotherapy preserves vision in patients with choroidal neovascular membrane associated with pathologic myopia. Younger patients and eyes with higher refractive error are more likely to benefit from treatment.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Choroidal Neovascularization / diagnosis
  • Choroidal Neovascularization / etiology
  • Choroidal Neovascularization / therapy*
  • Female
  • Fluorescein Angiography
  • Follow-Up Studies
  • Fovea Centralis
  • Fundus Oculi
  • Humans
  • Hyperthermia, Induced / methods*
  • Male
  • Middle Aged
  • Myopia / complications*
  • Myopia / diagnosis
  • Prospective Studies
  • Time Factors
  • Treatment Outcome
  • Visual Acuity