Highly regio- and stereoselective intermolecular tandem reaction to synthesize chloro-substituted 1,3-butadienes

Chem Commun (Camb). 2010 Feb 21;46(7):1035-7. doi: 10.1039/b923464k. Epub 2010 Jan 14.

Abstract

A palladium catalyzed highly regio- and stereoselective intermolecular tandem reaction of alkynes, CuCl(2) and alkenes by a sequence of chloropalladation/Heck reaction to produce chloro-substituted 1,3-dienes is achieved.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemistry
  • Alkynes / chemistry
  • Butadienes / chemical synthesis
  • Butadienes / chemistry*
  • Catalysis
  • Chlorine / chemistry*
  • Halogenation
  • Palladium / chemistry
  • Stereoisomerism

Substances

  • Alkenes
  • Alkynes
  • Butadienes
  • Chlorine
  • Palladium
  • 1,3-butadiene