Abstract
Seven new compounds including three flavanone glycosides, visartisides A-C (1-3), three glycoside acyl esters, visartisides D-F (4-6), and one diphenylpropane glycoside, (4'-hydroxy-2',3',6',3''-tetramethoxy-1,3-diphenylpropane)-4''-O-beta-d-glucopyranoside (7), along with four known flavanone glycosides (8-11) were isolated from the leaves and stems of Viscum articulatum. The structure elucidation of 1-7 was based on spectroscopic data analysis. Biological evaluation showed that 1, 2, and 10 exhibited antioxidant activity using a DPPH method and that compounds 1, 3, and 11 were active in a lipopolysaccharide-induced nitric oxide assay.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antioxidants / chemistry
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Antioxidants / pharmacology
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Biphenyl Compounds / pharmacology
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Esters
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Flavanones / chemistry
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Flavanones / isolation & purification*
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Flavanones / pharmacology
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Glycosides / chemistry
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Glycosides / isolation & purification*
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Glycosides / pharmacology
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Lipopolysaccharides / pharmacology
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Macrophages / drug effects
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Mice
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Molecular Structure
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Nerve Tissue / cytology
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Nerve Tissue / drug effects
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Nitric Oxide / antagonists & inhibitors
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Nitric Oxide / biosynthesis
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Picrates / pharmacology
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Plant Leaves / chemistry
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Plant Stems / chemistry
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Plants, Medicinal / chemistry*
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Stereoisomerism
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Taiwan
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Viscum / chemistry*
Substances
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Antioxidants
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Biphenyl Compounds
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Esters
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Flavanones
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Glycosides
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Lipopolysaccharides
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Picrates
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Nitric Oxide
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1,1-diphenyl-2-picrylhydrazyl
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flavanone