Insights on novel biologically active natural products: 7-isopentenyloxycoumarin

Nat Prod Commun. 2009 Dec;4(12):1755-60.

Abstract

7-Isopentenyloxycoumarin is a prenyloxyphenylpropanoid derivative found in low concentration in a restricted number of plant families (Apiaceae, Asteraceae, and Rutaceae). Synthetic schemes were recently developed enabling sufficient quantities of the title coumarin to be obtained in order to evidence its valuable biological effects, mainly as an anti-cancer agent. The aim of this review is to examine the phytochemical and pharmacological properties of this compound.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Anti-Inflammatory Agents / pharmacology
  • Antimutagenic Agents / isolation & purification
  • Antimutagenic Agents / pharmacology
  • Antineoplastic Agents, Phytogenic / chemistry*
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Coumarins / chemistry*
  • Coumarins / isolation & purification
  • Humans
  • Muscle Relaxants, Central / pharmacology
  • Plants / chemistry*

Substances

  • 7-isopentenyloxycoumarin
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Antimutagenic Agents
  • Antineoplastic Agents, Phytogenic
  • Coumarins
  • Muscle Relaxants, Central