Abstract
Four new 2-arylbenzofuran derivatives, moracins V-Y (1-4), together with two known compounds, moracin N (5) and moracin P (6), were isolated from the leaves of Morus alba L. Their structures were elucidated by spectroscopic analysis. Moracins X (3) and Y (4) represent unusual substituted group compared with 2-arylbenzofuran derivatives, which were isolated from the genus Morus. Compounds 2-5 were evaluated for cytotoxicity against several human cancer cell lines.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / analysis*
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology*
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Benzofurans / analysis*
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Benzofurans / isolation & purification
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Benzofurans / pharmacology*
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Cell Line, Tumor
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Cell Survival / drug effects
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Humans
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Molecular Structure
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Morus / chemistry*
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Neoplasms / drug therapy
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Plant Leaves / chemistry
Substances
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Antineoplastic Agents, Phytogenic
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Benzofurans