Bordetella pertussis clones identified by multilocus variable-number tandem-repeat analysis

Jacob Kurniawan; Ram P Maharjan; Wai Fong Chan; Peter R Reeves; Vitali Sintchenko; Gwendolyn L Gilbert; Frits R Mooi; Ruiting Lan

doi:10.3201/eid1602.081707

Bordetella pertussis clones identified by multilocus variable-number tandem-repeat analysis

Emerg Infect Dis. 2010 Feb;16(2):297-300. doi: 10.3201/eid1602.081707.

Authors

Jacob Kurniawan¹, Ram P Maharjan, Wai Fong Chan, Peter R Reeves, Vitali Sintchenko, Gwendolyn L Gilbert, Frits R Mooi, Ruiting Lan

Affiliation

¹ University of New South Wales, Sydney, New South Wales, Australia.

Abstract

Multilocus variable-number tandem-repeat analysis (MLVA) of 316 Bordetella pertussis isolates collected over 40 years from Australia and 3 other continents identified 66 MLVA types (MTs), including 6 predominant MTs. Typing of genes encoding acellular vaccine antigens showed changes that may be vaccine driven in 2 MTs prevalent in Australia.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Australia / epidemiology
Bordetella pertussis / genetics*
Gene Frequency
Genotype
Global Health
Humans
Minisatellite Repeats*
Whooping Cough / epidemiology
Whooping Cough / microbiology*