Diabetes and cognitive decline: investigating the potential influence of factors related to health disparities

J Aging Health. 2010 Apr;22(3):292-306. doi: 10.1177/0898264309357445. Epub 2010 Jan 26.

Abstract

Objective: The authors investigated whether factors related to health disparities--race, rural residence, education, perceived racial discrimination, vascular disease, and health care access and utilization--may moderate the association between diabetes and cognitive decline.

Method: Participants were 624 community-dwelling older adults (49% African American and 49% rural) who completed in-home mini-mental state examination at baseline and 4-year follow-up.

Results: Diabetes at baseline predicted four-year cognitive decline in regression models adjusted for a number of possible confounds. Only perceived discrimination and health utilization showed significant interaction effects with diabetes. Among African Americans who reported experiencing racial discrimination, there was a stronger relationship between diabetes and cognitive decline. Among participants who reported absence of visiting a physician within the past 6 months, the association between diabetes and cognitive decline was substantially larger.

Discussion: Findings suggest that factors related to health disparities may influence cognitive outcomes among older adults with diabetes.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Age Factors
  • Aged
  • Black or African American
  • Cognition
  • Cognition Disorders / etiology*
  • Cognition Disorders / pathology
  • Confidence Intervals
  • Diabetes Complications*
  • Diabetes Mellitus / pathology*
  • Female
  • Health Services Accessibility
  • Health Status Disparities*
  • Health Status Indicators
  • Humans
  • Interview, Psychological
  • Logistic Models
  • Male
  • Models, Statistical
  • Odds Ratio
  • Psychometrics
  • Risk Factors
  • Self Report
  • United States