An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis

J Pediatr Endocrinol Metab. 2009 Nov;22(11):1087-90. doi: 10.1515/jpem.2009.22.11.1087.

Abstract

Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well known manifestation of marked hypokalemia. Here, we report a case of primary hyperaldosteronism due to unilateral aldosterone-producing adenoma in a 14 year-old girl who developed rhabdomyolysis following hypokalemia. To our knowledge, this is the first case of adrenocortical adenoma presenting with rhabdomyolysis in a child.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adrenal Cortex Neoplasms / metabolism*
  • Adrenal Cortex Neoplasms / pathology
  • Adrenal Cortex Neoplasms / therapy
  • Adrenal Glands / diagnostic imaging
  • Adrenalectomy
  • Adrenocortical Adenoma / metabolism*
  • Adrenocortical Adenoma / pathology
  • Adrenocortical Adenoma / therapy
  • Aldosterone / metabolism*
  • Combined Modality Therapy
  • Female
  • Humans
  • Hypokalemia / complications
  • Hypokalemia / metabolism
  • Hypokalemia / pathology
  • Mineralocorticoid Receptor Antagonists / therapeutic use
  • Rhabdomyolysis / metabolism*
  • Rhabdomyolysis / pathology
  • Rhabdomyolysis / therapy
  • Spironolactone / therapeutic use
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Mineralocorticoid Receptor Antagonists
  • Spironolactone
  • Aldosterone