A cautionary note on the correct structure assignment of phytoprostanes and the emergence of a new prostane ring system

Ullrich Jahn; Jean-Marie Galano; Thierry Durand

doi:10.1016/j.plefa.2009.10.005

A cautionary note on the correct structure assignment of phytoprostanes and the emergence of a new prostane ring system

Prostaglandins Leukot Essent Fatty Acids. 2010 Feb-Mar;82(2-3):83-6. doi: 10.1016/j.plefa.2009.10.005. Epub 2010 Jan 22.

Authors

Ullrich Jahn¹, Jean-Marie Galano, Thierry Durand

Affiliation

¹ Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo namesti 2, 16610 Prague, Czech Republic. jahn@uochb.cas.cz

PMID: 20097050
DOI: 10.1016/j.plefa.2009.10.005

Abstract

Considerable confusion exists about the correct structural representation of phytoprostanes (PhytoP). Improper use of the different nomenclature systems leads to incorrect structure assignment of PhytoP, which results in wrong synthetic approaches to these molecules and may lead to wrong rationalization of biological activity. A new prostane ring system was found, which is proposed to be termed L(1)-PhytoP or L(2)-IsoP, respectively.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Fatty Acids, Unsaturated / chemistry*
Fatty Acids, Unsaturated / classification*
Molecular Structure
Plants / chemistry
Structure-Activity Relationship

Substances

Fatty Acids, Unsaturated