Interplay between hydrido/dihydrogen and amine/amido ligands in ruthenium-catalyzed transfer hydrogenation of ketones

Alexandre Picot; Hellen Dyer; Antoine Buchard; Audrey Auffrant; Laure Vendier; Pascal Le Floch; Sylviane Sabo-Etienne

doi:10.1021/ic902339j

Interplay between hydrido/dihydrogen and amine/amido ligands in ruthenium-catalyzed transfer hydrogenation of ketones

Inorg Chem. 2010 Feb 15;49(4):1310-2. doi: 10.1021/ic902339j.

Authors

Alexandre Picot¹, Hellen Dyer, Antoine Buchard, Audrey Auffrant, Laure Vendier, Pascal Le Floch, Sylviane Sabo-Etienne

Affiliation

¹ CNRS, LCC (Laboratoire de Chimie de Coordination), 205 Route de Narbonne, F-31077 Toulouse, France.

PMID: 20095639
DOI: 10.1021/ic902339j

Abstract

This work describes the synthesis of three key intermediates of Noyori-type catalytic systems that are active precatalysts for the transfer hydrogenation of acetophenone. Isolation of the cationic chloro(dihydrogen) complex [RuCl(H(2))(H(2)NNPP)(PCy(3))][BArf(4)] provides a facile synthetic route to the corresponding cationic and neutral hydrido complexes, and the series highlights the links between hydride/dihydrogen and amine/amido ligands in neutral and cationic species.