Abstract
Ceramic powders from fossil deposits were thoroughly characterized from the material point of view and sintered to produce massive components. The raw material, a mixture of apatite minerals, feldspars, and quartz, seems ideally suitable to obtain a biologically compatible glass ceramic. Preliminary in vitro tests of proliferation and adhesion of MG63 human osteoblast-like cell line on a selected sample are encouraging. Results are correlated with sintering conditions and phase composition: the fossil can be sintered to almost full density at temperatures as low as 900 °C and seems to quickly promote cell activation with respect to hydroxylapatite.
MeSH terms
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Aluminum Silicates / chemistry
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Aluminum Silicates / isolation & purification
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Animals
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Apatites / chemistry
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Apatites / isolation & purification
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Biocompatible Materials / chemistry*
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Biocompatible Materials / isolation & purification
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Bone Substitutes / chemistry
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Bone Substitutes / isolation & purification
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Cell Adhesion
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Cell Line
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Cell Proliferation
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Cell Survival
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Ceramics / chemistry
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Ceramics / isolation & purification
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Fossils*
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Hot Temperature
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Humans
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In Vitro Techniques
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Materials Testing
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Microscopy, Confocal
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Microscopy, Electron, Scanning
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Orthopedic Procedures
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Osteoblasts / cytology
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Potassium Compounds / chemistry
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Potassium Compounds / isolation & purification
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Powder Diffraction
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Powders
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Quartz / chemistry
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Quartz / isolation & purification
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Spectroscopy, Fourier Transform Infrared
Substances
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Aluminum Silicates
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Apatites
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Biocompatible Materials
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Bone Substitutes
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Potassium Compounds
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Powders
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feldspar
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Quartz