Evaluation of three immunochromatographic assays for detection of Legionella pneumophila serogroup 1 antigen in urine samples

Rev Esp Quimioter. 2009 Dec;22(4):207-9.

Abstract

The Uni-Gold, the SAS and the Binax NOW immunochromatographic test (ICT) urinary antigen assays for the qualitative detection of Legionella pneumophila serogroup 1 were compared using 39 unfrozen and nonconcentrated urine samples from patients with Legionnaires disease (LD). The Uni-Gold antigen test detected the urinary antigen in 41% (16/39), the SAS antigen test in 61.5% (24/39), and the Binax NOW antigen test in 74.3% (29/39). The Binax NOW ICT assay showed the best results when detecting L. pneumophila urinary antigen.

MeSH terms

  • Antigens, Bacterial / urine*
  • Enzyme-Linked Immunosorbent Assay
  • Epidemics
  • Humans
  • Immunochemistry
  • Legionella pneumophila / chemistry*
  • Legionnaires' Disease / diagnosis*
  • Legionnaires' Disease / immunology
  • Legionnaires' Disease / urine*
  • Spain / epidemiology

Substances

  • Antigens, Bacterial