Alkaloids from Sophora flavescens Aition

Fitoterapia. 2010 Sep;81(6):524-7. doi: 10.1016/j.fitote.2010.01.008. Epub 2010 Jan 15.

Abstract

Although the quinolizidine alkaloids and flavonoids, the main active components of the traditional Chinese medicine Sophora flavescens, have been largely investigated, a new matrine alkaloid derivative 9alpha-hydroxy-7,11-dehydromatrine (1) and a rare 1,4-diazaindan-type alkaloid flavascensine (17), together with 15 known alkaloids, were isolated from S. flavescens. The structures were established on the basis of spectroscopic techniques.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry
  • Alkaloids / isolation & purification*
  • Drugs, Chinese Herbal / chemistry
  • Heterocyclic Compounds, 4 or More Rings / chemistry
  • Heterocyclic Compounds, 4 or More Rings / isolation & purification
  • Molecular Structure
  • Plants, Medicinal / chemistry
  • Quinolizidines / chemistry
  • Quinolizidines / isolation & purification*
  • Sophora / chemistry*

Substances

  • 9alpha-hydroxy-7,11-dehydromatrine
  • Alkaloids
  • Drugs, Chinese Herbal
  • Heterocyclic Compounds, 4 or More Rings
  • Quinolizidines