[Functional MRI in schizophrenia. Diagnostics and therapy monitoring of cognitive deficits of schizophrenic patients by functional MRI]

Radiologe. 2010 Feb;50(2):131-5. doi: 10.1007/s00117-009-1895-y.
[Article in German]

Abstract

Cognitive impairments are core psychopathological components of the symptomatic of schizophrenic patients. These dysfunctions are generally related to attention, executive functions and memory. This report provides information on the importance of using functional magnetic resonance imaging (fMRI) for the diagnostics and therapy monitoring of the different subtypes of cognitive dysfunctions. Furthermore, it describes the typical differences in the activation of individual brain regions between schizophrenic patients and healthy control persons. This information should be helpful in identifying the deficit profile of each patient and create an individual therapy plan.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Antipsychotic Agents / therapeutic use*
  • Attention / drug effects
  • Attention / physiology
  • Brain Mapping / methods
  • Cerebral Cortex / drug effects
  • Cerebral Cortex / physiopathology*
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / drug therapy
  • Cognition Disorders / physiopathology*
  • Cognitive Behavioral Therapy*
  • Combined Modality Therapy
  • Dominance, Cerebral / drug effects
  • Dominance, Cerebral / physiology
  • Executive Function / drug effects
  • Executive Function / physiology
  • Frontal Lobe / drug effects
  • Frontal Lobe / physiopathology
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Memory / drug effects
  • Memory / physiology
  • Neuropsychological Tests
  • Parietal Lobe / drug effects
  • Parietal Lobe / physiopathology
  • Prefrontal Cortex / drug effects
  • Prefrontal Cortex / physiopathology
  • Reference Values
  • Schizophrenia / diagnosis*
  • Schizophrenia / drug therapy
  • Schizophrenia / physiopathology*
  • Schizophrenic Psychology*
  • Young Adult

Substances

  • Antipsychotic Agents