Abstract
Steroid hormones control many aspects of animal physiology and behaviour. They are highly regulated, among other mechanisms, by post-translational modifications of the transcription factors involved in their synthesis and response. In the present review, we will focus on the influence of SUMO (small ubiquitin-related modifier) and ubiquitin modifications on the function of transcription factors involved in adrenal cortex formation, steroidogenesis and the hormonal response.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adrenal Cortex / anatomy & histology
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Adrenal Cortex / physiology
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Animals
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Humans
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Protein Processing, Post-Translational*
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Receptors, Cytoplasmic and Nuclear / metabolism
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Receptors, Steroid / metabolism
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Signal Transduction / physiology
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Small Ubiquitin-Related Modifier Proteins / metabolism*
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Steroids / metabolism*
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Transcription Factors / metabolism
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Ubiquitin / metabolism*
Substances
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Receptors, Cytoplasmic and Nuclear
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Receptors, Steroid
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Small Ubiquitin-Related Modifier Proteins
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Steroids
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Transcription Factors
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Ubiquitin