Abstract
Moderate forms of 21-hydroxylase deficiency (D21OH-NC), the so-called non-classical or late-onset forms are a frequently reported cause of hyperandrogenism in women [1-5]. The purpose of this collective and synthetic work was to provide the endocrinologist, gynecologist and dermatologist with consensual information so as to detect the maximum cases with acceptable cost-benefit ratio and to define the main lines of optimal patient management, given the data currently available in medical literature.
Copyright (c) 2009 Elsevier Masson SAS. All rights reserved.
MeSH terms
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Adrenal Hyperplasia, Congenital / diagnosis
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Adrenal Hyperplasia, Congenital / drug therapy*
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Adrenal Hyperplasia, Congenital / epidemiology
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Adrenal Hyperplasia, Congenital / genetics
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Adrenal Insufficiency / complications
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Adrenal Insufficiency / diagnosis
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Cosyntropin
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Female
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Genetic Counseling
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Glucocorticoids / therapeutic use
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Hirsutism / etiology
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Hirsutism / therapy
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Hormone Replacement Therapy
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Humans
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Hyperandrogenism / diagnosis
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Hyperandrogenism / drug therapy*
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Hyperandrogenism / enzymology*
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Hyperandrogenism / epidemiology
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Hyperandrogenism / genetics*
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Infertility, Female / etiology
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Steroid 21-Hydroxylase / genetics
Substances
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Glucocorticoids
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Cosyntropin
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Steroid 21-Hydroxylase