Diastereoselective gamma-vinyl butyrolactone synthesis via gold catalyzed cyclization of allylic acetate

Chem Commun (Camb). 2010 Jan 28;46(4):577-9. doi: 10.1039/b913348h. Epub 2009 Dec 4.

Abstract

An efficient method for the preparation of polysubstituted gamma-vinyl butyrolactones was developed through gold catalyzed highly diastereoselective cyclization of the malonate substituted allylic acetates.