[The heterogeneity of the ospa gene of Borrelia garinii and Borrelia afzelii in western Siberia and Mongolia]

Mol Gen Mikrobiol Virusol. 2009:(4):18-22.
[Article in Russian]

Abstract

48 full-length Borrelia garinii and Borrelia afzelii from West Siberia and Mongolia ospA gene nucleotide sequences was determined. Four groups of Borrelia garinii were revealed using the analysis of nucleotide sequences. The most variable ospA gene region was demonstrated to be included in region where the antigenic determinants of protein were encoded. High homology level was shown for nucleotide sequences corresponding to isolates of Borrelia afzelii.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens, Surface / genetics*
  • Bacterial Outer Membrane Proteins / genetics*
  • Bacterial Vaccines / genetics*
  • Borrelia burgdorferi Group / genetics*
  • Genetic Variation*
  • Lipoproteins / genetics*
  • Mongolia
  • Sequence Homology, Nucleic Acid*
  • Siberia

Substances

  • Antigens, Surface
  • Bacterial Outer Membrane Proteins
  • Bacterial Vaccines
  • Lipoproteins
  • OspA protein