Antibiotic regimen including linezolid for treating prosthetic valve endocarditis with cerebral embolism due to methicillin-susceptible Staphylococcus aureus after failure with oxacillin and teicoplanin

P Brugraro; F Eseme; E Morelli; M Fiscon; G Rosini; F Belussi; F Ebo; A Petrucci; P Tenderini; E Raise

Antibiotic regimen including linezolid for treating prosthetic valve endocarditis with cerebral embolism due to methicillin-susceptible Staphylococcus aureus after failure with oxacillin and teicoplanin

Infez Med. 2009 Dec;17(4):240-3.

Authors

P Brugraro¹, F Eseme, E Morelli, M Fiscon, G Rosini, F Belussi, F Ebo, A Petrucci, P Tenderini, E Raise

Affiliation

¹ Department of Cardiology, Civil Hospital, Venice, Italy.

PMID: 20046105

Abstract

A case of prosthetic valve endocarditis due to methicillin susceptible Staphylococcus aureus (MSSA) with cerebral metastatic seeding is described. The patient is a 61 year old man with diabetes mellitus, chronic renal failure and previous bacterial endocarditis. Despite appropriate MSSA therapy, the patient was eventually cured with the introduction of linezolid, without needing surgical intervention.

Publication types

Case Reports

MeSH terms

Acetamides / therapeutic use*
Anti-Infective Agents / therapeutic use*
Aortic Valve / surgery*
Endocarditis, Bacterial / drug therapy*
Endocarditis, Bacterial / etiology*
Heart Valve Prosthesis / adverse effects*
Humans
Intracranial Embolism / drug therapy*
Linezolid
Male
Methicillin-Resistant Staphylococcus aureus*
Oxacillin / therapeutic use*
Oxazolidinones / therapeutic use*
Staphylococcal Infections / drug therapy*
Teicoplanin / therapeutic use*
Treatment Outcome

Substances

Acetamides
Anti-Infective Agents
Oxazolidinones
Teicoplanin
Linezolid
Oxacillin