Evaluation of the effects of dietary supplementation with fish oil omega-3 fatty acids on weight bearing in dogs with osteoarthritis

J Am Vet Med Assoc. 2010 Jan 1;236(1):67-73. doi: 10.2460/javma.236.1.67.

Abstract

Objective: To evaluate the effects of a food supplemented with fish oil omega-3 fatty acids on weight bearing in dogs with osteoarthritis.

Design: Randomized, double-blinded, controlled clinical trial.

Animals: 38 client-owned dogs with osteoarthritis examined at 2 university veterinary clinics.

Procedures: Dogs were randomly assigned to receive a typical commercial food (n = 16) or a test food (22) containing 3.5% fish oil omega-3 fatty acids. On day 0 (before the trial began) and days 45 and 90 after the trial began, investigators conducted orthopedic evaluations and force-plate analyses of the most severely affected limb of each dog, and owners completed questionnaires to characterize their dogs' arthritis signs.

Results: The change in mean peak vertical force between days 90 and 0 was significant for the test-food group (5.6%) but not for the control-food group (0.4%). Improvement in peak vertical force values was evident in 82% of the dogs in the test-food group, compared with 38% of the dogs in the control-food group. In addition, according to investigators' subjective evaluations, dogs fed the test food had significant improvements in lameness and weight bearing on day 90, compared with measurements obtained on day 0.

Conclusions and clinical relevance: At least in the short term, dietary supplementation with fish oil omega-3 fatty acids resulted in an improvement in weight bearing in dogs with osteoarthritis.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biomechanical Phenomena
  • Dog Diseases / diet therapy*
  • Dog Diseases / pathology
  • Dog Diseases / physiopathology
  • Dogs
  • Double-Blind Method
  • Fatty Acids, Omega-3 / therapeutic use*
  • Female
  • Fish Oils / administration & dosage
  • Fish Oils / chemistry
  • Lameness, Animal / diet therapy*
  • Lameness, Animal / pathology
  • Male
  • Osteoarthritis / diet therapy
  • Osteoarthritis / pathology
  • Osteoarthritis / physiopathology
  • Osteoarthritis / veterinary*
  • Prospective Studies
  • Range of Motion, Articular
  • Treatment Outcome
  • Weight-Bearing / physiology*

Substances

  • Fatty Acids, Omega-3
  • Fish Oils