Abstract
Chicks that have undergone long-term selection for low body weight responded to intracerebroventricular amylin injection with reduced food intake at a dose considerably lower and with a greater magnitude suppression than those selected for high body weight. Behaviors unrelated to ingestion were not affected. These data support the thesis of correlated amylin system responses to selection for low or high body weight, with possible implications to other species.
Copyright 2009 Elsevier B.V. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Age Factors
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Amyloid / pharmacology*
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Analysis of Variance
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Animals
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Animals, Newborn
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Anorexia / chemically induced*
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Appetite Depressants / pharmacology*
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Body Weight / drug effects*
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Body Weight / genetics
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Chickens
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Dose-Response Relationship, Drug
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Exploratory Behavior / drug effects
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Feeding Behavior / drug effects
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Injections, Intraventricular / methods
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Islet Amyloid Polypeptide
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Time Factors
Substances
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Amyloid
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Appetite Depressants
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Islet Amyloid Polypeptide