Recent insight into the pathogenicity mechanisms of the emergent pathogen Photorhabdus asymbiotica

Sónia C P Costa; Carolina Varela Chavez; Grégory Jubelin; Alain Givaudan; Jean-Michel Escoubas; Michel Brehélin; Robert Zumbihl

doi:10.1016/j.micinf.2009.12.003

Recent insight into the pathogenicity mechanisms of the emergent pathogen Photorhabdus asymbiotica

Microbes Infect. 2010 Mar;12(3):182-9. doi: 10.1016/j.micinf.2009.12.003. Epub 2009 Dec 23.

Authors

Sónia C P Costa¹, Carolina Varela Chavez, Grégory Jubelin, Alain Givaudan, Jean-Michel Escoubas, Michel Brehélin, Robert Zumbihl

Affiliation

¹ INRA, UMR 1133 Laboratoire EMIP, Montpellier, France.

PMID: 20034588
DOI: 10.1016/j.micinf.2009.12.003

Abstract

Photorhabdus asymbiotica is unique among the entomopathogenic bacteria of this genus in also being able to infect humans, leading to its isolation from some clinical samples. Recent comparative genomics data and the results of studies of interactions between bacteria and cells provide insight into the adaptation of this bacterium to its new niche, the human body.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Bacterial Proteins / genetics
Genome, Bacterial
Humans
Photorhabdus / genetics
Photorhabdus / pathogenicity*
Virulence
Virulence Factors / genetics

Substances

Bacterial Proteins
Virulence Factors