Carotid artery stenosis quantification: concordance analysis between radiologist and semi-automatic computer software by using Multi-Detector-Row CT angiography

Eur J Radiol. 2011 Jul;79(1):80-4. doi: 10.1016/j.ejrad.2009.11.025. Epub 2009 Dec 23.

Abstract

Purpose: Carotid artery stenosis quantification is still considered a leading parameter in the choice of the therapeutic option. Our purpose was to asses the concordance between radiologist and a semi-automatic computer software in the stenosis quantification of carotid artery studied by using a Multi-Detector-Row CT angiography (MDCTA).

Methods and material: 45 patients studied by using a 40-detector row CT scanner were retrospectively analyzed. Carotid artery stenosis was quantified by one high experienced radiologist in vessel analysis and by using a dedicated software. Carotid artery stenosis was calculated according to the ECST method. Bland-Altman statistics was used to measure the inter- and intra-concordance between radiologist and software and correlation coefficient between measures were performed by using nonparametric Spearmann correlation statistic. A p value<0.05 was considered to mean statistical significance.

Results: A strength correlation according to linear regression (correlation Spearman'ρ coefficient=0.975; p<0.0001) between radiologist and software of vessel analysis was observed. Between first and second stenosis of carotid artery quantification performed by radiologist and software of vessel analysis we observed a Spearman'ρ coefficient=0.943 (p<0.0001) and a Spearman'ρ coefficient=0.9879; (p<0.0001) respectively.

Conclusions: Our results indicated that there is a strength correlation according to linear regression between stenosis of carotid artery quantification performed by radiologist and semi-automatic software. Reproducibility between measurements performed by semi-automatic software are higher compared to radiologist.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Angiography / methods*
  • Carotid Stenosis / diagnostic imaging*
  • Contrast Media
  • Female
  • Humans
  • Iopamidol / analogs & derivatives
  • Linear Models
  • Male
  • Middle Aged
  • Radiographic Image Interpretation, Computer-Assisted
  • Retrospective Studies
  • Software*
  • Statistics, Nonparametric
  • Tomography, X-Ray Computed / methods*

Substances

  • Contrast Media
  • iomeprol
  • Iopamidol