Shell crosslinked nanoparticles carrying silver antimicrobials as therapeutics

Chem Commun (Camb). 2010 Jan 7;46(1):121-3. doi: 10.1039/b916559b. Epub 2009 Nov 9.

Abstract

Amphiphilic polymer nanoparticles loaded with silver cations or/and N-heterocyclic carbene-silver complexes were assessed as antimicrobial agents against Gram-negative pathogens Escherichia coli and Pseudomonas aeruginosa.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / chemistry*
  • Cross-Linking Reagents / chemistry
  • Escherichia coli / drug effects
  • Heterocyclic Compounds / chemistry
  • Methane / analogs & derivatives
  • Methane / chemistry
  • Microbial Sensitivity Tests
  • Nanoparticles / chemistry*
  • Pseudomonas aeruginosa / drug effects
  • Silver / antagonists & inhibitors*

Substances

  • Anti-Infective Agents
  • Cross-Linking Reagents
  • Heterocyclic Compounds
  • carbene
  • Silver
  • Methane