Abstract
A homogeneous assay is reported using Ru(phen)(2)(dppz)(2+) and a K(+)-binding aptamer for the selective and sensitive detection of a target oligonucleotide and potassium ions, based on reduction in fluorescence emission according to the formation of the G-quadruplex structure from the aptamer in the presence of K(+).
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Aptamers, Nucleotide / analysis*
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Aptamers, Nucleotide / chemistry
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Cations / chemistry
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G-Quadruplexes
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Potassium / chemistry*
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Sequence Analysis, DNA / methods*
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Spectrometry, Fluorescence / methods*
Substances
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Aptamers, Nucleotide
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Cations
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Potassium