A fluorescent heteroditopic ligand responding to free zinc ion over six orders of magnitude concentration range

Lu Zhang; Christopher S Murphy; Gui-Chao Kuang; Kristin L Hazelwood; Manuel H Constantino; Michael W Davidson; Lei Zhu

doi:10.1039/b918729d

A fluorescent heteroditopic ligand responding to free zinc ion over six orders of magnitude concentration range

Chem Commun (Camb). 2009 Dec 21:(47):7408-10. doi: 10.1039/b918729d. Epub 2009 Nov 4.

Authors

Lu Zhang¹, Christopher S Murphy, Gui-Chao Kuang, Kristin L Hazelwood, Manuel H Constantino, Michael W Davidson, Lei Zhu

Affiliation

¹ Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306-4390, USA.

PMID: 20024244
DOI: 10.1039/b918729d

Abstract

A fluorescent heteroditopic ligand useful in live-cell imaging studies responds to free zinc ion concentration over a range of six orders of magnitude in a buffered aqueous solution via dual-channel fluorescence.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Cations / chemistry
Cell Survival
Fluorescent Dyes / chemistry*
HeLa Cells
Humans
Ligands
Molecular Structure
Zinc / chemistry*

Substances

Cations
Fluorescent Dyes
Ligands
Zinc