Abstract
Palladium-catalyzed monofluoromethylation of substituted 2-bromo-1,3-dienes using fluorobis(phenylsulfonyl)methane (FBSM) as a pronucleophile gave previously unknown monofluoromethylated allenes in high yields, which are the isosteres of biologically attractive allenic alcohols.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkadienes / chemical synthesis*
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Bromine Compounds / chemistry
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Catalysis
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Fluorine / chemistry*
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Hydrocarbons, Fluorinated / chemistry*
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Methane / analogs & derivatives*
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Methane / chemistry
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Methylation
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Molecular Structure
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Palladium / chemistry*
Substances
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Alkadienes
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Bromine Compounds
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Hydrocarbons, Fluorinated
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fluorobis(phenylsulfonyl)methane
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Fluorine
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propadiene
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Palladium
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Methane