Enteral nutrition for severe malnutrition in chronic intestinal pseudo-obstruction

Nutrition. 2010 May;26(5):502-5. doi: 10.1016/j.nut.2009.07.012. Epub 2009 Dec 16.

Abstract

Objective: Chronic intestinal pseudo-obstruction (CIPO) is a rare intestinal motility disorder. A prolonged avoidance of food due to fear of aggravation of postprandial symptoms leads to severe malnutrition. We report a case of a 21 y old man who was diagnosed as CIPO with a history of recurrent intestinal colic and obstructive symptoms, slow transit type of constipation, bilateral hydronephrosis (non-obstructive), motor dysphagia without any evidence of demonstrable mechanical obstruction. Our aim was to keep his post prandial symptoms to a minimum and nutritionally build him up with enteral nutrition (EN).

Methods: He had life threatening malnutrition (BMI of 11 kg/m(2)) and significant postprandial distension with an intake more than 100 ml, compromising the quality of life. In view of a normal absorptive function of the gut, TPN was ruled out and the patient was treated with enteral nutrition (oral & tube) only. The EN regimen followed was ad libitum oral intake along with nocturnal NG tube feeding. Initially a full strength semi-elemental formula at 50 ml/hour was given, later shifted to polymeric formula at 100 ml/hour. Serum levels of magnesium, phosphate and potassium were regularly monitored to prevent refeeding syndrome. He ws constantly motivated, counseled and monitored.

Result: With a gradual increase in the intake from 300 Kcal to 1400 Kcal he was discharged. Eight months from discharge he had a weight of 58 kg (BMI = 22.3 kg/m(2)), with resumption of normal activities and marked improvement in the quality of life.

Conclusion: Carefully planned EN along with motivation, psychological support and regular monitoring are the keys to nutritional management in CIPO.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Body Mass Index
  • Chronic Disease
  • Constipation / etiology
  • Deglutition Disorders / etiology
  • Energy Intake
  • Enteral Nutrition*
  • Food
  • Gastrointestinal Motility
  • Humans
  • Intestinal Pseudo-Obstruction / complications*
  • Intestinal Pseudo-Obstruction / physiopathology
  • Male
  • Malnutrition / etiology*
  • Malnutrition / therapy*