Direct arylations of 2H-indazoles on water

Org Lett. 2010 Jan 15;12(2):224-6. doi: 10.1021/ol902537d.

Abstract

The efficient palladium-catalyzed synthesis of a range of substituted 2H-Indazoles via C-H arylation is reported. Reactions are performed on water and provide a direct and mild route toward 2,3-diaryl indazoles of widespread biological significance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Indazoles / chemical synthesis
  • Indazoles / chemistry*
  • Molecular Structure
  • Palladium / chemistry
  • Water / chemistry*

Substances

  • Indazoles
  • Water
  • Palladium