[Recent advances in treatment of glial scar-induced inhibition of nerve regeneration]

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2009 Nov;38(6):639-43. doi: 10.3785/j.issn.1008-9292.2009.06.015.
[Article in Chinese]

Abstract

Glial scar formed by central nervous system (CNS) injury is the main inhibitory barrier of nerve regeneration. How to promote axonal regeneration after injury,how to accelerate neural network reconstruction and how to improve brain function recovery have become a hot problem to be solved in the field of neuroscience. This article focuses on the recent advances of therapeutic strategies for axonal regeneration.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Astrocytes / pathology*
  • Brain Injuries / pathology
  • Brain Injuries / physiopathology*
  • Cicatrix / prevention & control*
  • Humans
  • Nerve Regeneration
  • Neuroglia / pathology
  • Neuronal Plasticity / physiology*
  • Neurons / physiology
  • Proteoglycans / metabolism
  • Spinal Cord Injuries / pathology
  • Spinal Cord Injuries / physiopathology*

Substances

  • Proteoglycans