Abstract
Tetraspanins are small integral membrane proteins that are known to control a variety of cellular processes, including signaling, migration and cell-cell fusion. Research over the past few years established that they are also regulators of various steps in the HIV-1 replication cycle, but the mechanisms through which these proteins either enhance or repress virus spread remain largely unknown.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Animals
-
Antigens, CD / physiology*
-
HIV-1 / physiology*
-
Host-Pathogen Interactions
-
Humans
-
Membrane Glycoproteins / physiology*
-
Platelet Membrane Glycoproteins / physiology*
-
Tetraspanin 28
-
Tetraspanin 29
-
Tetraspanin 30
-
Transcription, Genetic
-
Virus Internalization
-
Virus Replication*
Substances
-
Antigens, CD
-
CD63 protein, human
-
CD81 protein, human
-
CD9 protein, human
-
Membrane Glycoproteins
-
Platelet Membrane Glycoproteins
-
Tetraspanin 28
-
Tetraspanin 29
-
Tetraspanin 30