In this review we systematized literature data illuminating problems of prevention and correction of cognitive disorders in patients with arterial hypertension (AH). On the basis of results of multicenter randomized studies we have demonstrated close interrelationship between cardiac and cerebral pathology and value of treatment of concomitant neurologic and cardiovascular disorders for prevention of cognitive disturbances in patients with AH. We have shown rational approach to planning antihypertensive therapy and to degree of arterial pressure (AP) lowering in patients with AH, including those with cerebrovascular pathology having high risk of development of stroke and dementia. It has been also shown that in patients with AH calcium antagonists, angiotensin II receptor blockers, and inhibitors of angiotensin converting enzyme posses definite advantages over antihypertensive drugs from other classes in prevention of dementia and less severe cognitive disturbances.