Palladium-catalyzed tandem amination reaction for the synthesis of 4-quinolones

Tiankun Zhao; Bin Xu

doi:10.1021/ol902626d

Palladium-catalyzed tandem amination reaction for the synthesis of 4-quinolones

Org Lett. 2010 Jan 15;12(2):212-5. doi: 10.1021/ol902626d.

Authors

Tiankun Zhao¹, Bin Xu

Affiliation

¹ Department of Chemistry, Shanghai University, Shanghai 200444, China.

PMID: 20000580
DOI: 10.1021/ol902626d

Abstract

An efficient palladium-catalyzed tandem amination approach was developed in one step to afford functionalized 4-quinolones in good to excellent yields from easily accessible o-haloaryl acetylenic ketones and primary amines.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

4-Quinolones / chemical synthesis*
4-Quinolones / chemistry
Amination
Amines / chemistry
Catalysis
Ketones / chemistry
Molecular Structure
Palladium / chemistry*

Substances

4-Quinolones
Amines
Ketones
Palladium