No evidence for linkage of autosomal dominant proximal spinal muscular atrophies to chromosome 5q markers

Hum Genet. 1991 Jan;86(3):317-8. doi: 10.1007/BF00202419.

Abstract

Two recent articles have reported the linkage of a gene for recessive spinal muscular atrophy (SMA) on the chromosome region 5q11.2-13.3. Our data show no linkage of the dominantly inherited forms of SMA to this chromosome region.

MeSH terms

  • Chromosome Mapping
  • Chromosomes, Human, Pair 5*
  • Female
  • Genes, Dominant*
  • Genetic Linkage*
  • Genetic Markers
  • Humans
  • Male
  • Muscular Atrophy, Spinal / genetics*
  • Recombination, Genetic

Substances

  • Genetic Markers