A preliminary study for investigating idiopatic normal pressure hydrocephalus by means of statistical parameters classification of intracranial pressure recordings

Annu Int Conf IEEE Eng Med Biol Soc. 2009:2009:2629-32. doi: 10.1109/IEMBS.2009.5335371.

Abstract

The objective of this study is to investigate Id-iopatic Normal Pressure Hydrocephalus (INPH) through a multidimensional and multiparameter analysis of statistical data obtained from accurate analysis of Intracranial Pressure (ICP) recordings. Such a study could permit to detect new factors, correlated with therapeutic response, which are able to validate a predicting significance for infusion test. The algorithm developed by the authors computes 13 ICP parameter trends on each of the recording, afterward 9 statistical information from each trend is determined. All data are transferred to the datamining software WEKA. According to the exploited feature-selection techniques, the WEKA has revealed that the most significant statistical parameter is the maximum of Single-Wave-Amplitude: setting a 27 mmHg threshold leads to over 90% of correct classification.

MeSH terms

  • Adult
  • Aged
  • Algorithms
  • Biomedical Engineering / methods
  • Data Interpretation, Statistical
  • Electronic Data Processing
  • Equipment Design
  • Female
  • Humans
  • Hydrocephalus, Normal Pressure / diagnosis*
  • Hydrocephalus, Normal Pressure / physiopathology
  • Intracranial Pressure / physiology*
  • Male
  • Middle Aged
  • Pattern Recognition, Automated
  • Signal Processing, Computer-Assisted
  • Software
  • Spinal Puncture / methods
  • Transducers, Pressure