Concomitant use of clopidogrel and proton pump inhibitors or cimetidine after acute myocardial infarction would increase the risk of re-infarction

Am J Gastroenterol. 2009 Dec;104(12):3116-7. doi: 10.1038/ajg.2009.525.
No abstract available

Publication types

  • Letter

MeSH terms

  • Alleles
  • Anti-Ulcer Agents / adverse effects
  • Anti-Ulcer Agents / therapeutic use*
  • Aryl Hydrocarbon Hydroxylases / genetics
  • Cimetidine / adverse effects
  • Cimetidine / therapeutic use*
  • Clopidogrel
  • Cytochrome P-450 CYP2C19
  • Drug Interactions
  • Female
  • Humans
  • Male
  • Myocardial Infarction / genetics
  • Myocardial Infarction / prevention & control*
  • Odds Ratio
  • Platelet Aggregation Inhibitors / adverse effects
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Proton Pump Inhibitors / adverse effects
  • Proton Pump Inhibitors / therapeutic use*
  • Taiwan
  • Ticlopidine / adverse effects
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / therapeutic use

Substances

  • Anti-Ulcer Agents
  • Platelet Aggregation Inhibitors
  • Proton Pump Inhibitors
  • Cimetidine
  • Clopidogrel
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Ticlopidine