Abstract
Seven new tetranortriterpenoids (1-7), named chisonimbolinins A-G, were isolated from twigs of Chisocheton paniculatus. Their structures were elucidated on the basis of extensive spectroscopic analyses, and the structure of 1 was confirmed by a single-crystal X-ray diffraction study. Cytotoxic activity of compounds 1-7 was evaluated using HeLa and SMMC-7721 tumor cell lines.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Antineoplastic Agents, Phytogenic / chemistry
-
Antineoplastic Agents, Phytogenic / isolation & purification*
-
Antineoplastic Agents, Phytogenic / pharmacology
-
Crystallography, X-Ray
-
Drug Screening Assays, Antitumor
-
Drugs, Chinese Herbal / chemistry
-
Drugs, Chinese Herbal / isolation & purification*
-
Drugs, Chinese Herbal / pharmacology
-
HeLa Cells
-
Humans
-
Limonins / chemistry
-
Limonins / isolation & purification*
-
Limonins / pharmacology
-
Meliaceae / chemistry*
-
Molecular Conformation
-
Molecular Structure
Substances
-
Antineoplastic Agents, Phytogenic
-
Drugs, Chinese Herbal
-
Limonins