This study highlights the socio-demographics and death circumstances of victims of fatal road traffic injuries (RTIs) in one Iranian province. A representative sample of cases was selected from a national register and interviews were conducted with the victims' family members. The study shows that there is a strong association between victim attributes (e.g. sex, age, occupation, education or marital status) and category of road-user. Although men are over-represented in all categories, women die above all as car passengers or pedestrians. Deaths of vulnerable road-users are more frequent among the younger and older age groups. Two-thirds of all deaths occurred before arrival at the hospital and 11% of the victims received ambulance transport. The patterns of fatal RTIs observed in the province differ somewhat from the rest of Iran and other low- and middle-income countries. Not only pre- but also post-crash counter-measures could help save lives in the region.